• Nattokinase
  • Nattokinase
  • Nattokinase
  • Nattokinase

Nattokinase

Keep Ingredients competitively supplies Nattokinase with hot-sales specifications of 2000fu, 5000fu & 20000fu, with production of Fermentation.

Nattokinase (NK) is an alkaline serine protease secreted by Bacillus subtilis (natto), which has the advantages of long half-life, strong specificity, minimal side effects, and direct oral administration.
  • Nattokinase
  • Nattokinase

Description

Keep Ingredients competitively supplies Nattokinase with hot-sales specifications of 2000fu, 5000fu & 20000fu, with production of Fermentation.

Nattokinase (NK) is an alkaline serine protease secreted by Bacillus subtilis (natto), which has the advantages of long half-life, strong specificity, minimal side effects, and direct oral administration.


ITEMS OF ANALYSIS

SPECIFICATIONS

RESULTS

Appearance

Activity of enzyme Loss on drying

Loss on ignition

Heavy metals (as Pb) 

Heavy metals (as As)

White powder

2000FU ≤8.0%

≤5.0%

<5 ppm 

<3 ppm

Conform 

2053FU  3.3%

2.30%

<5 ppm 

<3 ppm

Microbiology

Total Plante Count

 TE

Yeast and Mould

E.coli/25g

Salmonella/25g

<1000cfu/g 

<30 cfu/g   

<100 cfu/g 

Absent

Absent

<5600cfu/g 

<30 cfu/g     

<10 cfu/g     

Absent

Absent

Storage

STORED HUMIDITY PROTECTED

(RH LESS THAN 60) AT TEMPERATURE BELOW 25℃

Shelf Life

2 Years when Properly Stored


Functional Positioning for Cardiovascular and Nutritional Product Developers
Nattokinase is positioned as a specialized enzymatic ingredient targeting cardiovascular health support in nutraceutical formulations. Manufactured by established nutritional ingredients suppliers, it serves companies requiring reliable enzyme supplements with proven efficacy. The enzyme’s activity enhances fibrinolytic function, supporting healthy blood flow and circulation. Its minimal side effect profile and direct oral administration suitability further refine its applicability for heart-health-focused dietary supplements. This makes nattokinase a compatible choice for manufacturers aiming to meet consumer demand for natural, enzyme-based cardiovascular wellness products within regulated markets.

Technical Features and Quality Assurance Standards
Produced via controlled fermentation from Bacillus subtilis (natto), nattokinase is available in customizable enzyme potency grades—2000FU, 5000FU, and 20000FU—to meet specific formulation needs. The product exhibits a long enzyme half-life and strong substrate specificity, ensuring consistent bioactivity. Strict quality control measures include moisture content regulation (≤8.0% loss on drying), heavy metal limits (Pb <5 ppm, As <3 ppm), and microbiological safety verified through third-party testing. Its white powder form allows seamless integration into nutritional blends, maintaining integrity with a two-year shelf life under recommended storage. These specifications affirm nattokinase’s suitability for precision formulation by professional nutraceutical ingredient manufacturers.

Industry Applications and Integration Benefits
This enzyme ingredient is widely applied by nutrition distributors and formulated into dietary supplements supporting cardiovascular wellness and fibrinolytic function. It integrates effectively with other nutritional components for enzyme therapy or heart health supplements, expanding product portfolios in natural alternatives to synthetic anticoagulants. Research-driven product lines utilize nattokinase’s proven enzymatic activity to enhance metabolic and cardiovascular benefits. The ingredient’s reliable quality and compliance with safety standards facilitate streamlined integration in nutraceutical manufacturing workflows, contributing measurable value within global supplement supply chains.


Use Scenarios

Application in Cardiovascular Nutraceutical Formulations
In cardiovascular nutraceutical manufacturing environments, nattokinase serves as a core enzymatic ingredient enhancing fibrinolytic activity to promote healthy blood flow. Its enzymatic properties meet stringent safety and potency standards required by nutritional ingredients suppliers in this sector. The ingredient’s compatibility with other active compounds allows formulation of effective cardiovascular support products compliant with regulatory requirements. Integration into production workflows is facilitated by its stable white powder format and multiple activity grades, enabling precise dosing and consistent quality within large-scale supplement manufacturing systems.

Role in Enzyme Therapy and Natural Anticoagulant Product Lines
Nattokinase is utilized by nutraceutical ingredient manufacturers developing enzyme therapy supplements and natural anticoagulant alternatives to synthetic drugs. In these operational contexts, its long half-life and substrate specificity provide efficacy advantages that support therapeutic nutrition strategies. The enzyme’s minimal side effect profile aligns with safety compliance standards, critical in clinical or lifestyle health regimes. Workflow integration benefits from product consistency and third-party testing assurances, enabling seamless inclusion in high-value functional nutrition products targeting metabolic and cardiovascular health markets.


FAQ

What types of nattokinase enzyme activity grades are available?
We offer nattokinase enzyme powders in multiple activity grades, specifically 2000FU, 5000FU, and 20000FU. These options allow for precise formulation across a variety of nutritional and nutraceutical applications, meeting diverse potency requirements for bulk ingredient buyers.

How does Keep Ingredients ensure the quality and safety of nattokinase?
Our nattokinase undergoes rigorous quality assurance, including in-house and third-party testing for heavy metals and microbiological contaminants. This thorough process guarantees product consistency and safety for nutraceutical ingredient manufacturers and nutrition distributors globally.

Can nattokinase be customized for large-scale production needs?
Yes, Keep Ingredients supports custom production plans to match your batch size and activity grade requirements. We collaborate closely with top domestic factories, ensuring every batch adheres to strict quality standards and product specifications suited for B-end customers.

What are the recommended storage conditions for maintaining nattokinase activity?
To preserve enzyme integrity, nattokinase should be stored below 25°C with relative humidity under 60%. Adhering to these conditions ensures a stable shelf life of two years, supporting reliable supply chains for nutritional ingredients suppliers and their downstream clients.

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