High-Bioavailability Vitamin E TPGS

Name: 100% Water-soluble Vitamin E Polyethylene GlycolSuccinate (TPGS)
Brand: Keep Ingredients - proteins, extracts, powders
Rating: 5 (1 reviews)

100% Water-soluble Vitamin E Polyethylene GlycolSuccinate (TPGS)

For over a decade, KEEP INGREDIENTS has supplied premium-grade Vitamin E TPGS (D-α-Tocopheryl Polyethylene Glycol Succinate) — a USP39-certified, multifunctional ingredient revolutionizing bioavailability in nutraceuticals, functional foods, and cosmetics. Our TPGS (CAS 9002-96-4) transforms lipid-soluble actives into water-miscible solutions, unlocking unprecedented formulation potential.

Description

Core Advantages for Functional Applications

1. Superior Solubility & Bioavailability

TPGS converts fat-soluble compounds (e.g., vitamins, curcumin, CoQ10) into clear aqueous solutions, increasing solubility by 2–16x3. Its micelle-forming structure enhances intestinal absorption, making it ideal for low-fat diets or age-related nutrient uptake challenges.

Enables transparent fortification of beverages, gummies, and dairy—no cloudiness or separation79.

2. Multifunctional Performance

Stability & Emulsification: Heat-stable up to 200°C, TPGS extends shelf-life in functional foods and cosmetics at just 1% usage (vs. traditional surfactants)3.

Synergistic Nutrient Protection: Acts as an antioxidant shield, recycling other antioxidants like Vitamin C and protecting sensitive actives during processing18.

3. Safety & Compliance

USP39 Certified: Rigorous third-party testing confirms:

≥25% D-α-tocopherol content (exceeding USP standards)

Ultra-low heavy metals (Pb <0.1ppm, Hg <0.01ppm) and microbial contaminants (<10 CFU/g)1.

Globally compliant with FDA, EU, and China regulations for foods, supplements, and cosmetics.

Industry Applications: Function-Focused Solutions

📊 Nutraceuticals & Supplements
Enhances absorption of vitamins, curcumin, and botanicals in capsules, softgels, and powders.

Ideal for aging populations and consumers seeking proactive wellness support—key drivers in Europe’s $27B supplement market (5.92% CAGR)25.

🥤 Functional Foods & Beverages
Fortifies clear drinks, yogurts, and gummies without compromising texture or appearance.

Aligns with trends for gut health (e.g., probiotic co-formulations) and energy products—cited as top innovation areas at Vitafoods Europe 202379.

✨ Cosmetics & Personal Care
Stabilizes anti-aging serums and sunscreens by protecting against UV-induced oxidation.

Reduces lipid peroxidation in haircare formulations, maintaining follicle integrity1.

Why Partner with KEEP INGREDIENTS?

Decade of Expertise: Consistent quality and technical support for global clients.
Future-Ready Supply: ISO-certified facility, with full traceability documentation.
Market Edge: Leverage TPGS to:
Accelerate novel delivery formats (sprays, nanoparticles, solid dispersions).

CAS No.	9002-96-4
Item	Specification	Result	Analysis Method
Description	Off-white or yellowish waxy solid	Off-white to Light yellow paste	Visual
Identification	Meets the requirements	Conforms	GC
(D- α-tocopherol)Assay	≥25.0%	27.7%	GC
Solubility in water	20% Min (Clear solution)	Conforms	USP Method
Acidity	≤0.27mL	0.20mL	USP Method
Specific Rotation	≥+24.0°	+28.4°	USP<781S>
Heavy Metals Cadmium Arsenic Lead Mercury	≤10 ppm ≤1 ppm ≤1 ppm ≤3 ppm ≤0.1ppm	<10ppm <0.01ppm <0.040ppm <0.1ppm <0.010ppm	USP<231> ICP-MS ICP-MS ICP-MS AAS
Residual solve Ethyl acetate Ethanol	≤3000ppm ≤5000ppm	39ppm 106ppm	USP<467>
Micro. Test Aerobic Plate Count Yeast &Mold Salmonella E.Coli	≤1000CFU/g ≤100CFU/g Negative Negative	<10CFU/g <10CFU/g Negative Negative	USP<61> USP<61> USP<61> USP<61>
Conclusion: The product complies with USP39.
Packaging & Storage: Store in tightly closed containers at room temperature. Protected from moisture and pest infestation.

Product Advantages

Design and Integration Flexibility of Vitamin E TPGS

The molecular design of this vitamin E derivative embodies a polyethylene glycol succinate backbone that confers full water solubility and surfactant qualities, representing a significant upgrade over fat-soluble analogs. This chemical architecture allows seamless integration into aqueous matrices without requiring organic solvents or emulsifiers, simplifying formulations and reducing excipient loads. The product’s consistency in physical and chemical parameters, assured by direct supply from a reputable TPGS manufacturer, eases scale-up and quality assurance processes. These design strengths cater specifically to pharmaceutical and nutritional production lines demanding robust ingredient performance and system compatibility.

Optimized Antioxidant Performance and Formulation Efficiency

From a performance standpoint, this water soluble vitamin E provides enhanced bioavailability, enabling faster and more complete absorption pathways compared to standard vitamin E preparations. Its antioxidant stability ensures longer shelf life and sustained cellular protection effects in final products, critical for compliance with efficacy claims. Users benefit from its ease of incorporation into liquid and semi-solid dosing forms, reducing manufacturing complexity while improving end-product consistency. As a reliable vitamin e tpgs supplier, our offering maximizes formulation efficiency, ROI, and product value throughout development and commercialization stages.

FAQ

Is your 100% water-soluble Vitamin E Polyethylene Glycol Succinate (TPGS) suitable for custom formulation needs?

We offer Vitamin E TPGS that is highly versatile, supporting custom formulations across dietary supplements and pharmaceutical products. Our manufacturer-direct supply ensures reliable quality for tailored aqueous-based applications requiring enhanced solubility and bioavailability.

What distinguishes your Vitamin E TPGS from traditional fat-soluble vitamin E in terms of stability?

Our water soluble vitamin E in the form of Polyethylene Glycol Succinate (TPGS) provides improved antioxidant stability within aqueous environments, enhancing product shelf life and efficacy compared to fat-soluble vitamin E compounds that are less compatible with such formulations.

Can you assist with bulk order logistics and quality assurance for Vitamin E TPGS?

We maintain stringent quality control and provide direct manufacturer sourcing for Vitamin E TPGS, ensuring consistent purity and performance. Our team supports efficient logistics and supply reliability to meet large volume demands in nutritional and pharmaceutical production.

Does your Vitamin E TPGS support integration with other bioactives in complex delivery systems?

Yes, our Vitamin E TPGS formulation is designed to enhance the bioavailability of co-administered ingredients and is compatible with liposomal and co-loading delivery systems, making it ideal for complex nutraceutical and pharmaceutical products requiring synergistic antioxidant support.

100% Water-soluble Vitamin E Polyethylene GlycolSuccinate (TPGS)

Description

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