• Meso-Zeaxanthin 55% HPLC (Marigold Extract)
  • Meso-Zeaxanthin 55% HPLC (Marigold Extract)

Meso-Zeaxanthin 55% HPLC (Marigold Extract)

  • Core Macular Carotenoid & High Potency Assurance: Extracted from natural marigold flowers (Tagetes erecta L.) and precisely quantified via HPLC to guarantee Meso-Zeaxanthin content ≥ 55.0%, serving as the critical defense barrier for the ocular fovea in premium eye care formulations.

  • High Concentration & Low Dosage for Formula Space: Featuring a high active purity of 55%, the required single dosage in capsules, tablets, and multi-ingredient blends is extremely small, saving ample formulation space for synergistic ingredients (such as Lutein, Astaxanthin, and Anthocyanins).

  • Superior Physical Properties & Processing Ease: Features a 100% pass rate through 80 mesh fine powder with excellent flowability and ideal bulk density (loose density 0.4–0.7 g/ml, tapped density 0.6–1.0 g/ml), significantly improving blending uniformity for tableting and capsule filling.

  • Strict Solvent Residual & Ultra-Low Pesticide Controls: Utilizes a mild hexane and ethanol extraction process, keeping residual solvents (hexane ≤ 50 ppm, ethanol ≤ 500 ppm) and organochlorine pesticide residues (666, DDT, Quintozine ≤ 0.1 ppm) strictly below international regulatory limits.

  • Reliable B2B Supply Chain & Full Export Support: Keep Ingredients offers flexible low-MOQ options, free sample testing support, complete export customs clearance documentation (COA, Certificate of Origin, etc.), and smooth global logistics channels.

Description



Product Description

Meso-Zeaxanthin 55% (Marigold Extract) is a high-purity, high-concentration natural carotenoid raw material. Among the carotenoid deposits in the human eye's macular region, Meso-Zeaxanthin is specifically concentrated in the fovea centralis—the area responsible for the sharpest vision. It acts as the primary shield to neutralize harmful high-energy blue light, quench singlet oxygen, and protect against oxidative damage.

Our Meso-Zeaxanthin 55% raw material is extracted from premium marigold flowers (Tagetes erecta L.) and undergoes refined purification and rigorous HPLC testing to guarantee an active content ≥ 55.0%. Appearing as a fine orange-red powder that 100% passes through an 80-mesh screen, it delivers outstanding powder uniformity and processing flowability. With its ultra-high active concentration of 55%, dietary supplement and functional food brands can achieve superior eye health efficacy with minimal dosage, making it the ideal choice for developing premium eye care products featuring triple macular pigment protection (Lutein + Zeaxanthin + Meso-Zeaxanthin).

Key Features & Highlights

  • 55% Ultra-High Active Purity: Standardized by High-Performance Liquid Chromatography (HPLC) to guarantee Meso-Zeaxanthin active content ≥ 55.0%, significantly reducing formulation volume and lowering manufacturing costs.

  • Targeted Foveal Protection: Directly replenishes the specific carotenoid concentrated in the most vision-critical area (fovea centralis), delivering robust protection against high-energy blue light and intense light stress.

  • Pure Marigold Origin: 100% derived from marigold flowers, aligning with Clean Label trends and the high standards of natural dietary supplements.

  • Superior Solid Oral Dosage Processing: Fine 80-mesh powder (100% pass rate) ensures uniform particle distribution and excellent dispersion, demonstrating superior blending consistency during high-speed tableting and hard capsule filling.

  • Rigorous Heavy Metal & Microbiological Limits: Total heavy metals ≤ 10 ppm, Arsenic < 2 ppm, Lead/Cadmium ≤ 1 ppm, Mercury ≤ 0.1 ppm; pathogenic bacteria (E. coli, Salmonella) strictly non-detectable, fully complying with strict European and American import standards.

Certificate of Analysis 

ITEMS SPECIFICATIONS
Appearance

Orange-red fine powder

Odor

Characteristic

Taste

Characteristic

Granular size

100% Through 80mesh

Meso-zeaxanthin content (HPLC)

≥ 55.0%

Loss on drying

≤ 5.0%

Residue on Ignition

≤ 5.0%

Loose density

0.4–0.7 g/ml

Tapped density

0.6–1.0 g/ml

Extract Solvent

Hexane & Ethanol

Residual Hexane

≤ 50 ppm

Residual Ethanol

≤ 500 ppm

Pesticide 666

≤ 0.1 ppm

Pesticide DDT

≤ 0.1 ppm

Pesticide Quintozine

≤ 0.1 ppm

Heavy Metals

≤ 10 ppm

Arsenic (As)

< 2 ppm

Lead (Pb)

≤ 1 ppm

Cadmium (Cd)

≤ 1 ppm

Mercury (Hg)

≤ 0.1 ppm

Total plate count

≤ 1000 cfu/g

Yeast & mold

≤ 100 cfu/g

Escherichia coli

Negative

Salmonella

Negative

Formulator's Guide & Processing Advantages

  • High Concentration Advantage: Because active purity reaches 55%, only a minimal amount of active material (typically a few milligrams) is required per capsule or tablet. This drastically reduces excipient volume usage and simplifies multi-ingredient formulation development.

  • Mixing Uniformity Management: Due to the small inclusion rate, geometric dilution (trituration) or pre-blending with main excipients such as microcrystalline cellulose or starch is recommended during solid dosage manufacturing to ensure 100% uniform dispersion in high-speed mixers.

  • Protection Against Light & Oxidation: Carotenoid structures are inherently sensitive to intense light, elevated temperatures, and oxygen. Avoid prolonged exposure to direct light during manufacturing. Finished product packaging should utilize light-barrier capsules or aluminum foil blister packs, optionally combined with antioxidants like Vitamin C or Vitamin E.

Applications

  • Premium Triple Macular Pigment Capsules: Co-formulated with Lutein and Zeaxanthin at golden ratios to recreate the complete carotenoid structure of the human macula, crafting high-end anti-aging eye health solutions.

  • Targeted Anti-Blue Light Formulas for Esports & Heavy Screen Users: Formulated for software engineers, esports professionals, and office workers exposed to high-energy shortwave blue light (LEDs, phones, computers), delivering targeted foveal blue-light filtering and eye fatigue recovery.

  • Preventive Supplements for Age-Related Macular Degeneration (AMD): Recognized in clinical nutrition, it is widely incorporated into formulas designed to protect against age-related vision decline, improve contrast sensitivity, and enhance night vision.

  • Concentrated Mini-Tablets & Multi-Nutrient Capsules: Leverages its 55% high-concentration advantage to integrate effortlessly into multi-vitamin softgels, mini-tablets, or daily nutrition packs without adding bulk.

  • Advanced Oral Skin Photoprotection & Photo-Aging Defense: Utilizes powerful singlet oxygen quenching capabilities, combining with collagen peptides, astaxanthin, and grape seed extract to block UV and high-energy visible light damage at the skin dermal layer.

Quality Assurance & Global Compliance

  • Strict Pesticide & Solvent Monitoring: Every batch undergoes Gas Chromatography (GC) analysis to strictly regulate residual solvents (hexane and ethanol) and organochlorine pesticides (666, DDT, Quintozine), ensuring full compliance with international clean label standards.

  • Heavy Metal & Microbiological Controls: Accurately quantified via Atomic Absorption Spectrometry (AAS) for heavy metals (Lead, Arsenic, Cadmium, Mercury). CP2010 standards ensure Total Plate Count ≤ 1000 cfu/g with zero pathogens for complete safety assurance.

  • Professional Vacuum Aluminum Foil Packaging: Packaged internally with 1kg or 5kg double-layer vacuum-sealed aluminum foil bags and externally with 25kg standard fiber drums, effectively shielding against light, oxygen, and moisture to ensure long-distance ocean shipping stability.

Why Choose Keep Ingredients?

Keep Ingredients is your trusted global partner for food nutrition ingredients and botanical extracts:

  • Extensive Global Export Expertise: Products exported to over 30 countries and regions worldwide, with deep familiarity with local regulations, quality standards, and customs entry requirements.

  • Smooth Logistics & Freight Forwarding Support: Long-term partnerships with professional freight forwarders enable rapid provision of Certificates of Origin (Form A/E), Health Certificates, COAs, and full export documentation for hassle-free customs clearance.

  • Flexible Low-MOQ Sourcing: Support flexible minimum order quantities, helping small-to-medium enterprises and new R&D projects reduce upfront testing costs and inventory pressure.

  • Free Samples & Technical Assistance: Free samples available for assay testing, formulation trials, and stability evaluations, backed by a professional technical team to answer processing and application queries.

FAQ

Q1: What is the difference between Meso-Zeaxanthin and standard Zeaxanthin?

A1: Both are stereoisomers, but they serve distinct functions in the human visual system. Standard Zeaxanthin is predominantly deposited in the peripheral macula, whereas Meso-Zeaxanthin is uniquely concentrated at the exact center of the macula (fovea centralis), offering superior high-energy blue light absorption and singlet oxygen quenching efficiency.

Q2: What are the advantages of choosing a high 55% concentration of Meso-Zeaxanthin?

A2: A high purity of 55% means you need a very small inclusion rate (e.g., 10–20mg yields 5.5–11mg of pure active material). This significantly saves valuable space inside capsules or tablets, making it ideal for complex, multi-ingredient formulations.

Q3: How do I ensure mixing uniformity during solid oral dosage production with such a low inclusion rate?

A3: Our material features an 80-mesh uniform particle size (100% pass rate). For commercial manufacturing, geometric dilution (trituration) is recommended: pre-blend Meso-Zeaxanthin with a portion of microcrystalline cellulose or starch before mixing into the main batch to ensure high lot-to-lot uniformity.

Q4: Does your Meso-Zeaxanthin meet North American and European quality and pesticide standards?

A4: Yes, completely. Every batch is rigorously tested; residual solvents (hexane ≤ 50 ppm, ethanol ≤ 500 ppm) and pesticide residues (e.g., 666, DDT) are maintained far below USP and European Pharmacopoeia (EP) monograph limits.

Q5: What is the recommended synergistic formula for Meso-Zeaxanthin?

A5: The classic golden ratio is the "Triple Macular Pigment Formula" (Meso-Zeaxanthin + Lutein + Zeaxanthin), typically combined in a 10mg : 10mg : 2mg ratio (or adapted from AREDS2 derivative studies) to provide comprehensive protection across all retinal macular zones.

Q6: Can you provide free samples for HPLC assay testing?

A6: Yes. Keep Ingredients provides complimentary samples for HPLC potency verification, dissolution testing, and stability evaluations. We also support low-MOQ trial orders to assist your new product R&D.

Ready to Elevate Your Eye Health Formulations? Request Free Samples Today!

Looking for a high-purity, stable, and globally compliant Meso-Zeaxanthin 55% ingredient to power your next premium eye care product? Keep Ingredients is here to support your success. Our expert team will respond within one hour to provide technical specifications, free sample kits, and tiered volume pricing.

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